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In re 疫苗之殤

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发表于 7-26-2018 16:47:14 | 显示全部楼层 |阅读模式
(1) Latin-English dictionary:
(a) in re (preposition; Latin, literally meaning "in the matter [of]")
https://en.wiktionary.org/wiki/in_re
(b) rē (n): "ablative singular of [noun feminine] rēs [thing, matter]"
https://en.wiktionary.org/wiki/re

(2) Bridged today reposts 郭现中, 疫苗之殤. 南方都市报, June 23, 2013, which I read for the first time. The report is reproduced at
https://www.facebook.com/notes/g ... A5/325217924285316/
(3) The report started with two photos of 卢佳润 and 董梓欣, each in vegetative state, following vaccination of "A群流脑" years before.

I am an immunologist by training, though I have since switched to law (as pro se, Latin for ). The images are shocking, but frankly I have doubts.
(4) 中國大陸地區嬰幼兒預防接種項目對照表. Taipei: 衛生福利部疾病管制署, undated
www.cdc.gov.tw/downloadfile.aspx?fid=A3FE533FD8EAEAB3

, which is very helpful, in explaining
(a) what DaPT stands for in English: "Diphtheria and tetanus toxoid with acellular pertussis(DTaP)"

Take notice of "Diphtheria and tetanus toxoid with whole cell pertussis vaccine(DTwP)."
(b) "A群流脑疫苗/ A群流脑多糖疫苗(Men A)” in PRC is "Menigoccoccal A" in English.
(c) "口服脊髓灰质炎疫苗/小儿麻痹糖丸/脊髓灰质炎三价疫苗/ 脊灰减毒活疫苗/脊灰疫苗" in PRC is "Oral Poliovirus vaccine(OPV)" in English.
(i) Of note, it appears that Taiwan also uses this, rather than inactivated polio vaccine. I say "appear" because the table does not list inactivated polio vaccine. But in 2010 Taiwan switched from oral 口服, attenuated 减毒 polio vaccine to intramuscular-injection 肌肉注射 inactivated 灭活 [Taiwan does not use this term, though] polio vaccine (as well as from DTwP to DTaP; see (5)). See
五合一疫苗Q&A. 疾病管制署 急性組, last updated on Dec 26, 2011
https://www.cdc.gov.tw/professio ... id=7054d8bdbe75ea3d
("本項疫苗可以同時預防白喉、破傷風、百日咳、小兒麻痺以及b型嗜血桿菌等五種幼兒傳染病,除將舊型三合一疫苗中的全細胞性百日咳成分,改為非細胞性百日咳,可大幅減少接種後發生接種部位紅腫、疼痛或發燒等不良反應的機率;另外也改用不活化小兒麻痺疫苗取代原口服小兒麻痺疫苗,以因應小兒麻痺根除之全球策略,並可避免機率極低的疫苗相關肢體麻痺型小兒麻痺症(VAPP)的發生")
(ii) Vaccine-derived Poliovirus; Questions and answers. Atlanta: CDC, undated
https://www.cdc.gov/vaccines/vpd ... poliovirus-faq.html
("What is a vaccine-derived poliovirus?  A vaccine-derived poliovirus (VDPV) is a strain of the weakened poliovirus that was initially included in oral polio vaccine (OPV) and that has changed over time and behaves more like the wild or naturally occurring virus. This means it can be spread more easily to people who are unvaccinated against polio and who come in contact with the stool or respiratory secretions, such as from a sneeze, of an infected person. These viruses may cause illness, including paralysis.  For this reason, the global eradication of polio requires stopping all OPV in routine immunization, as soon as possible after the eradication of wild poliovirus (WPV) transmission.  To protect against all three types of WPV [wild polio virus], the United States exclusively has used IPV since 2000")

So, America's exclusive use of IPV (inactivated polio vaccine) lasts only 18 years, and not because of concern over VAPP.
(iii) Vaccine-associated paralytic polio (VAPP) and vaccine-derived poliovirus (VDPV); Fact sheet. World Health Organization, 2015
said, "OPV is made with live attenuated (weakened) polioviruses that can result in a case of vaccine-associated paralytic polio (VAPP) in approximately 1 in 2.7 million doses of OPV."

(5) US Vaccine Names. Atlanta: CDC, undated
https://www.cdc.gov/vaccines/terms/usvaccines.html

has DT, DTsP (but not DTwP), IPV (but not OPV), Haemophilus influenzae type b (Hib), and meningococcal A and B.

* Haemophilus influenzae
https://en.wikipedia.org/wiki/Haemophilus_influenzae
("The bacterium was mistakenly considered to be the cause of influenza until 1933, when the viral cause of influenza became apparent * * * the presence of the capsule in encapsulated type b (Hib), a serotype causing conditions such as epiglottitis, is known to be a major factor in virulence. Their capsule allows them to resist phagocytosis and complement-mediated lysis in the nonimmune host. * * * Most strains of H. influenzae are opportunistic pathogens; that is, they usually live in their host without causing disease, but cause problems only when other factors (such as a viral infection, reduced immune function or chronically inflamed tissues, e.g. from allergies) create an opportunity)

is a Gram-negative bacterium, whereas we now know that all influenza are caused by influenza virus.

(6)
(a) "Twelve serogroups (strains) [of Neisseria meningitidis (also termed meningococcus)] exist with six having the potential to cause a major epidemic - A, B, C, X, Y and W135 are responsible for virtually all cases of the disease in humans." en.wikipedia.org for eningococcal_disease
(b) Meningococcal ACWY. Ask the Experts, undated
www.immunize.org/askexperts/experts_meningococcal_acwy.asp
("N. meningitidis is classified into at least 13 serogroups based on characteristics of the polysaccharide capsule. Most invasive disease (such as meningitis and sepsis) is caused by serogroups A, B, C, W, and Y. The relative importance of serogroups depends on geographic location and other factors such as age. Serogroups B, C, and Y are the most frequent causes of disease in the U.S., each accounting for about one third of reported cases. Serogroup A is common in Sub-Saharan Africa but is rare in the US")
(c) Meningococcal Vaccination: What Everyone Should Know. Atalanta: CDC, undated
https://www.cdc.gov/vaccines/vpd/mening/hcp/index.html
("There are two types of meningococcal vaccines available in the United States:
• Conjugate vaccines (Menactra® and Menveo®) [against serotypes ACWY]
• Serogroup B (recombinant) vaccines (Bexsero® and Trumenba®)" )

The meningococcal vaccines (ACWY or B) are made of proteins (either from basterium or from recombinant technique), not of bacterium itself. I have no id4ea ho China makes or made meningococcal vaccines.

(7) Even in US, where DPT vaccine has no bacterium, shit may happens
https://www.cdc.gov/vaccines/hcp/vis/vis-statements/dtap.html
("Severe Problems (Very Rare)")

, but it can not possibly caused by bacterium, because the vaccines in US has no bacterium.

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